Learn about assisted hatching, a procedure used during IVF to help the embryo implant in the uterus. Weigh the pros and cons, and understand the risks and success rates before deciding if it’s right for you.
What is Assisted Hatching?
Assisted hatching is a procedure that is sometimes used during in vitro fertilization (IVF) to help the embryo implant in the lining of the uterus. During assisted hatching, a small hole is made in the outer layer of the embryo, called the zona pellucida, to allow the embryo to “hatch” and begin to grow. This procedure is typically performed when the zona pellucida is thicker than normal, which can make it more difficult for the embryo to hatch and implant.
Pros and Cons of Assisted Hatching
There are both pros and cons to assisted hatching. Some of the potential benefits include:
- Improved implantation rates: Some studies have shown that assisted hatching can improve the chances of the embryo implanting in the uterus, leading to a higher pregnancy rate.
- Increased success in certain groups: Assisted hatching may be more effective in certain groups of people, such as those with a history of implantation failure or those using frozen embryos.
On the other hand, there are also some potential drawbacks to assisted hatching, including:
- Risks to the embryo: Assisted hatching involves manipulating the embryo, which carries some risk of damage.
- Additional cost: Assisted hatching is an additional procedure that may not be covered by insurance, leading to additional costs for the patient.
- Mixed results: Some studies have shown that assisted hatching has no significant impact on pregnancy rates, while others have shown a benefit. This inconsistency in results makes it difficult to predict the effectiveness of assisted hatching in any given situation.
Embryo and Blastocyst Stage
Assisted hatching is typically performed on embryos that are at the blastocyst stage, which is the final stage of development before implantation. At this stage, the embryo has formed a fluid-filled cavity and a group of cells called the inner cell mass, which will eventually become the baby. Assisted hatching may be less effective on earlier stage embryos, as the zona pellucida is not as developed and may be easier for the embryo to hatch on its own.
Implantation and Success Rates
The ultimate goal of assisted hatching is to improve the chances of the embryo implanting in the uterus. Implantation is the process by which the embryo attaches to the uterine lining and begins to grow. A successful implantation is necessary for pregnancy to occur.
The success rate of assisted hatching varies depending on a number of factors, including the age of the woman, the cause of infertility, and the quality of the embryos. Some studies have shown that assisted hatching can improve the chances of pregnancy, while others have shown no significant difference. It is important to discuss the potential benefits and risks of assisted hatching with a fertility specialist to determine if it is the right option for you.
